Born in Uruguay from immigrant European parents, Kohen studied Architecture at the Universidad de la Republica and Cambridge University. She resided in Brazil during the military rule years from 1976 to 1984. Back in Montevideo, she established her own practice and developed public and private, urban and architectural projects. In 1998 she won with her team, the competition for the Memorial in Remembrance of Disappeared Detained Prisoners, concluded in 2003 and now declared a National Historic Monument. Between 2014 and 2016 she participated as Advisor of the Design Team for the transformation of the ESMA Detention and Torture Center in Argentina, into a Site Museum, an ongoing judicial case. From 2003 to 2008 she served as Director the School of Architecture at the University of Florida, where she currently teaches, conducts Research and directs the UF Center for Hydro-generated Urbanism.